5C7O

Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase holo form with NAD+

Summary for 5C7O

• Entry DOI: 10.2210/pdb5c7o/pdb
• Related: 5C7L
• Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, testis-specific, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: human sperm gapdh metabolic enzyme sperm specific with nad+ cofactor, oxidoreductase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm : O14556
• Total number of polymer chains: 2
• Total formula weight: 74854.47

Authors

Betts, L.,Machius, M.,Danshina, P.,O'Brien, D. (deposition date: 2015-06-24, release date: 2016-03-09, Last modification date: 2023-11-15)

• Primary citation: Danshina, P.V.,Qu, W.,Temple, B.R.,Rojas, R.J.,Miley, M.J.,Machius, M.,Betts, L.,O'Brien, D.A.; Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme.; Mol. Hum. Reprod., 22:410-426, 2016; PubMed: 26921398; DOI: 10.1093/molehr/gaw016

Experimental method

X-RAY DIFFRACTION (1.729 Å)