5C7O
Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase holo form with NAD+
Summary for 5C7O
Entry DOI | 10.2210/pdb5c7o/pdb |
Related | 5C7L |
Descriptor | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | human sperm gapdh metabolic enzyme sperm specific with nad+ cofactor, oxidoreductase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : O14556 |
Total number of polymer chains | 2 |
Total formula weight | 74854.47 |
Authors | Betts, L.,Machius, M.,Danshina, P.,O'Brien, D. (deposition date: 2015-06-24, release date: 2016-03-09, Last modification date: 2023-11-15) |
Primary citation | Danshina, P.V.,Qu, W.,Temple, B.R.,Rojas, R.J.,Miley, M.J.,Machius, M.,Betts, L.,O'Brien, D.A. Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme. Mol. Hum. Reprod., 22:410-426, 2016 Cited by PubMed: 26921398DOI: 10.1093/molehr/gaw016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.729 Å) |
Structure validation
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