5C36

Crystal structure of GTA + UDP-C-Gal + DI

Summary for 5C36

Related5BXC 5C1G 5C1H 5C1L 5C38 5C3A 5C3B 5C3D 5C48 5C49 5C4B 5C4C 5C4D 5C4E 5C4F 5C47 5C8R
DescriptorHisto-blood group ABO system transferase, MANGANESE (II) ION, octyl 3-deoxy-2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-xylo-hexopyranoside, ... (5 entities in total)
Functional Keywordsglycosyltransferase deoxyinhibitor abo(h) blood-group system complex, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight35575.62
Authors
Gagnon, S.,Meloncelli, P.,Zheng, R.B.,Haji-Ghassemi, O.,Johal, A.R.,Borisova, S.N.,Lowary, T.L.,Evans, S.V. (deposition date: 2015-06-17, release date: 2015-09-23, Last modification date: 2020-01-08)
Primary citation
Gagnon, S.M.,Meloncelli, P.J.,Zheng, R.B.,Haji-Ghassemi, O.,Johal, A.R.,Borisova, S.N.,Lowary, T.L.,Evans, S.V.
High Resolution Structures of the Human ABO(H) Blood Group Enzymes in Complex with Donor Analogs Reveal That the Enzymes Utilize Multiple Donor Conformations to Bind Substrates in a Stepwise Manner.
J.Biol.Chem., 290:27040-27052, 2015
PubMed: 26374898 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M115.682401
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.55 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2257 0.3% 2.0% 12.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
170383
PDB entries from 2020-10-28