5BX7

PKA in complex with a benzothiophene fragment compound.

Summary for 5BX7

• Entry DOI: 10.2210/pdb5bx7/pdb
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 1-benzothiophen-3-ylmethanol, ... (6 entities in total)
• Functional Keywords: inhibitor, protein kinase, structure-guided, fragment-based, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm. Isoform 2: Cell projection, cilium, flagellum: P17612
• Total number of polymer chains: 2
• Total formula weight: 43577.60

Authors

Narayanan, D.,Alam, K.A.,Engh, R.A. (deposition date: 2015-06-08, release date: 2016-09-14, Last modification date: 2024-01-10)

• Primary citation: Narayanan, D.,Gani, O.A.,Alam, K.A.,Engh, R.A.; PKA based studies of ligand interactions with a methionine gatekeeper.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.89 Å)