5BX7
PKA in complex with a benzothiophene fragment compound.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 351 | 40888.5 | 1 | UniProt (P17612) Pfam (PF00069) | Homo sapiens (Human) | PKA C-alpha |
| 2 | B (B) | cAMP-dependent protein kinase inhibitor alpha | polymer | 20 | 2226.4 | 1 | UniProt (P61925) | Homo sapiens | PKI-alpha,cAMP-dependent protein kinase inhibitor,muscle/brain isoform |
| 3 | C (A) | 1-benzothiophen-3-ylmethanol | non-polymer | 164.2 | 1 | Chemie (4W1) | |||
| 4 | D, F (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 5 | E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence modifications
A: 0 - 349 (UniProt: P17612)
| PDB | External Database | Details |
|---|---|---|
| Phe 350 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43115.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 462.6 | |
| All* | Total formula weight | 43577.6 |
