5BW7

Crystal structure of nonfucosylated Fc Y296W mutant complexed with bis-glycosylated soluble form of Fc gamma receptor IIIa

Summary for 5BW7

• Entry DOI: 10.2210/pdb5bw7/pdb
• Descriptor: Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor III-A, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: immune system, complex, fc fragment, igg, receptor, cd16, gamma
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 75925.99

Authors

Isoda, Y.,Yagi, H.,Satoh, T.,Shibata-Koyama, M.,Masuda, K.,Satoh, M.,Kato, K.,Iida, S. (deposition date: 2015-06-06, release date: 2015-10-14, Last modification date: 2023-11-08)

• Primary citation: Isoda, Y.,Yagi, H.,Satoh, T.,Shibata-Koyama, M.,Masuda, K.,Satoh, M.,Kato, K.,Iida, S.; Importance of the Side Chain at Position 296 of Antibody Fc in Interactions with Fc gamma RIIIa and Other Fc gamma Receptors; Plos One, 10:e0140120-e0140120, 2015; PubMed: 26444434; DOI: 10.1371/journal.pone.0140120

Experimental method

X-RAY DIFFRACTION (3 Å)