5BW4

Crystal structure of the 16S rRNA (adenine(1408)-N(1))-methyltransferase W203A mutant with cosubstrate SAM from Catenulisporales acidiphilia

Summary for 5BW4

Entry DOI	10.2210/pdb5bw4/pdb
Related	5BW5
Descriptor	16S rRNA (adenine(1408)-N(1))-methyltransferase, S-ADENOSYLMETHIONINE (3 entities in total)
Functional Keywords	methyltransferase, ribosome, aminoglycoside resistance, transferase
Biological source	Catenulispora acidiphila
Total number of polymer chains	2
Total formula weight	57819.83
Authors	Witek, M.A.,Conn, G.L. (deposition date: 2015-06-05, release date: 2016-04-20, Last modification date: 2023-09-27)
Primary citation	Witek, M.A.,Conn, G.L. Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization. Nucleic Acids Res., 44:342-353, 2016 Cited by PubMed: 26609134 DOI: 10.1093/nar/gkv1306 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation