5BPP
Structure of human Leukotriene A4 hydrolase in complex with inhibitor 4AZ
Summary for 5BPP
Entry DOI | 10.2210/pdb5bpp/pdb |
Related | 5AEN |
Descriptor | Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ... (6 entities in total) |
Functional Keywords | inhibitor, complex, inflammation, enzyme, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P09960 |
Total number of polymer chains | 1 |
Total formula weight | 72402.17 |
Authors | |
Primary citation | Xiao, Q.,Dong, N.N.,Yao, X.,Wu, D.,Lu, Y.,Mao, F.,Zhu, J.,Li, J.,Huang, J.,Chen, A.,Huang, L.,Wang, X.,Yang, G.,He, G.,Xu, Y.,Lu, W.Q. Bufexamac ameliorates LPS-induced acute lung injury in mice by targeting LTA4H Sci Rep, 6:25298-25298, 2016 Cited by PubMed: 27126280DOI: 10.1038/srep25298 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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