5BPP

Structure of human Leukotriene A4 hydrolase in complex with inhibitor 4AZ

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Leukotriene A-4 hydrolase	polymer	631	71535.3	1	UniProt (P09960) Pfam (PF17900) Pfam (PF01433) Pfam (PF09127) In PDB	Homo sapiens (Human)	LTA-4 hydrolase,Leukotriene A(4) hydrolase
2	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	A	YTTERBIUM (III) ION	non-polymer		173.0	3	Chemie (YB)
4	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
5	A	2-(4-butoxyphenyl)-N-hydroxyacetamide	non-polymer		223.3	1	Chemie (A4Z)
6		water	water		18.0	243	Chemie (HOH)

Sequence modifications

A: 0 - 610 (UniProt: P09960)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	71535.3
Non-Polymers*	Number of molecules	6
	Total formula weight	866.8
All*	Total formula weight	72402.2

*Water molecules are not included.