5BNQ

Crystal structure of hRANKL-mRANK complex

Summary for 5BNQ

Entry DOI	10.2210/pdb5bnq/pdb
Descriptor	Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor receptor superfamily member 11A, PHOSPHATE ION, ... (6 entities in total)
Functional Keywords	rank, rankl, rankl-rank complex, tnfsf11, tnfrsf11a, tnf superfamily, cytokine
Biological source	Homo sapiens (Human) More
Cellular location	Isoform 1: Cell membrane; Single-pass type II membrane protein. Isoform 3: Cell membrane; Single-pass type II membrane protein. Isoform 2: Cytoplasm . Tumor necrosis factor ligand superfamily member 11, soluble form: Secreted : O14788 Cell membrane ; Single-pass type I membrane protein : O35305
Total number of polymer chains	2
Total formula weight	42758.80
Authors	Ren, J. (deposition date: 2015-05-26, release date: 2015-10-14, Last modification date: 2024-01-10)
Primary citation	Liu, C.,Zhao, Y.,He, W.,Wang, W.,Chen, Y.,Zhang, S.,Ma, Y.,Gohda, J.,Ishida, T.,Walter, T.S.,Owens, R.J.,Stuart, D.I.,Ren, J.,Gao, B. A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis. Sci Rep, 5:14150-14150, 2015 Cited by PubMed: 26412210 DOI: 10.1038/srep14150 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation