Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| A | 0006955 | biological_process | immune response |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 401 |
| Chain | Residue |
| A | GLN163 |
| A | GLN163 |
| A | GLN163 |
| A | VAL313 |
| A | VAL313 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 402 |
| Chain | Residue |
| A | LYS262 |
| A | LYS262 |
| A | LYS262 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 403 |
| Chain | Residue |
| A | TRP264 |
| A | HIS271 |
| A | THR261 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | LYS195 |
| A | LYS282 |
| R | LYS86 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 405 |
| Chain | Residue |
| A | HIS189 |
| A | ASP190 |
| A | ARG191 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 R 301 |
| Chain | Residue |
| A | GLN237 |
| A | MET239 |
| A | LYS257 |
| A | PHE272 |
| A | ASP300 |
| R | LYS97 |
| R | CYS125 |
| R | GLU126 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 R 302 |
| Chain | Residue |
| R | CYS113 |
| R | TRP121 |
| R | ASN147 |
| R | HOH401 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 R 303 |
| Chain | Residue |
| R | ALA117 |
| R | GLY118 |
| R | ASN131 |
| R | LEU144 |
| R | GLN145 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue NA R 304 |
| Chain | Residue |
| R | CYS134 |
| R | ALA135 |
| R | PHE138 |
| R | SER161 |
| R | VAL163 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue CL R 305 |
| Chain | Residue |
| R | HIS90 |
| R | LYS91 |
| R | PRO110 |
| R | ARG111 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue CL R 306 |
| Chain | Residue |
| R | HIS120 |
| R | ASN122 |
Functional Information from PROSITE/UniProt
| site_id | PS00652 |
| Number of Residues | 35 |
| Details | TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Ctqerh.Yehlgr.....C..Csr.Cepgkylssk..Ctpts..DSVC |
| Chain | Residue | Details |
| R | CYS35-CYS69 | |
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CaCtaGYhwnsdcecC |
| Chain | Residue | Details |
| R | CYS113-CYS128 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 149 |
| Details | Domain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 34 |
| Details | Repeat: {"description":"TNFR-Cys 1"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"TNFR-Cys 2"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 37 |
| Details | Repeat: {"description":"TNFR-Cys 3"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"TNFR-Cys 4"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 5 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"23039992","evidenceCode":"ECO:0000269"}]} |
