5AZ5

Crystal structure of human TLR8 in complex with MB-343

Summary for 5AZ5

• Entry DOI: 10.2210/pdb5az5/pdb
• Descriptor: Toll-like receptor 8, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: immune system, tlr8, adjuvant, vaccine adjuvants, innate immunity, glycosylation, viral infection, tlr
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 382394.16

Authors

Tanji, H.,Ohto, U.,Shimizu, T. (deposition date: 2015-09-27, release date: 2016-10-05, Last modification date: 2020-07-29)

• Primary citation: Tanji, H.,Ohto, U.,Shimizu, T.; Crystal structure of human TLR8 in complex with MB-343; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)