Summary for 5AYX
Entry DOI | 10.2210/pdb5ayx/pdb |
Descriptor | Nicotinate-nucleotide pyrophosphorylase [carboxylating] (2 entities in total) |
Functional Keywords | quinolinate phosphoribosyltransferase, nad biosynthesis, nadc, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 6 |
Total formula weight | 191680.03 |
Authors | Kang, G.B.,Kim, M.-K.,Im, Y.J.,Lee, J.H.,Youn, H.-S.,An, J.Y.,Lee, J.-G.,Fukuoka, S.-I.,Eom, S.H. (deposition date: 2015-09-14, release date: 2016-02-03, Last modification date: 2023-11-08) |
Primary citation | Youn, H.-S.,Kim, T.G.,Kim, M.-K.,Kang, G.B.,Kang, J.Y.,Lee, J.-G.,An, J.Y.,Park, K.R.,Lee, Y.,Im, Y.J.,Lee, J.H.,Eom, S.H. Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis Sci Rep, 6:19681-19681, 2016 Cited by PubMed: 26805589DOI: 10.1038/srep19681 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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