5AUY

Crystal structure of DAPK1 in complex with morin.

Summary for 5AUY

Related5AUT 5AUU 5AUV 5AUW 5AUX 5AUZ 5AV0 5AV1 5AV2 5AV3 5AV4
DescriptorDeath-associated protein kinase 1, 2-[2,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl)chromen-4-one (3 entities in total)
Functional Keywordsdeath-associated protein kinase 1, serine/threonine protein kinase, natural flavonoid, transferase
Biological sourceHomo sapiens (Human)
Cellular locationIsoform 1: Cytoplasm. Isoform 2: Cytoplasm P53355
Total number of polymer chains1
Total molecular weight34098.64
Authors
Yokoyama, T.,Mizuguchi, M. (deposition date: 2015-06-10, release date: 2015-10-07)
Primary citation
Yokoyama, T.,Kosaka, Y.,Mizuguchi, M.
Structural Insight into the Interactions between Death-Associated Protein Kinase 1 and Natural Flavonoids.
J.Med.Chem., 58:7400-7408, 2015
PubMed: 26322379 (PDB entries with the same primary citation)
DOI: 10.1021/acs.jmedchem.5b00893
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.252502.9%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution