5AQ1

Trypanosoma cruzi Glucose-6-phosphate Dehydrogenase in complex with G6P and NADPH

Summary for 5AQ1

• Entry DOI: 10.2210/pdb5aq1/pdb
• Descriptor: GLUCOSE-6-PHOSPHATE DEHYDROGENASE, 6-O-phosphono-beta-D-glucopyranose, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• Functional Keywords: oxidoreductase, pentose phosphate pathway, redox balance, chagas disease, g6pd, g6pdh.
• Biological source: TRYPANOSOMA CRUZI
• Total number of polymer chains: 3
• Total formula weight: 175878.02

Authors

Mercaldi, G.F.,Dawson, A.,Hunter, W.N.,Cordeiro, A.T. (deposition date: 2015-09-18, release date: 2016-07-20, Last modification date: 2024-01-10)

• Primary citation: Mercaldi, G.F.,Dawson, A.,Hunter, W.N.,Cordeiro, A.T.; The Structure of a Trypanosoma Cruzi Glucose-6-Phosphate Dehydrogenase Reveals Differences from the Mammalian Enzyme.; FEBS Lett., 590:2776-, 2016; PubMed: 27391210; DOI: 10.1002/1873-3468.12276

Experimental method

X-RAY DIFFRACTION (2.65 Å)