5AQ1

Trypanosoma cruzi Glucose-6-phosphate Dehydrogenase in complex with G6P and NADPH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	GLUCOSE-6-PHOSPHATE DEHYDROGENASE	polymer	509	57620.4	3	UniProt (Q4E0B2) Pfam (PF00479) Pfam (PF02781)	TRYPANOSOMA CRUZI
2	D, F, H (A, B, C)	6-O-phosphono-beta-D-glucopyranose	non-polymer		260.1	3	Chemie (BG6)
3	E, G, I (A, B, C)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	3	Chemie (NDP)
4	J, K, L (A, B, C)	water	water		18.0	253	Chemie (HOH)

Sequence modifications

A, B, C: 58 - 545 (UniProt: Q4E0B2)

PDB	External Database	Details
Met 37	-	expression tag
Gly 38	-	expression tag
His 39	-	expression tag
His 40	-	expression tag
His 41	-	expression tag
His 42	-	expression tag
His 43	-	expression tag
His 44	-	expression tag
Glu 45	-	expression tag
Asn 46	-	expression tag
Leu 47	-	expression tag
Tyr 48	-	expression tag
Phe 49	-	expression tag
Gln 50	-	expression tag
Gly 51	-	expression tag
His 52	-	expression tag
Met 53	-	expression tag
Ala 54	-	expression tag
Ser 55	-	expression tag
Gly 56	-	expression tag
Ser 57	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	172861.3
Non-Polymers*	Number of molecules	6
	Total formula weight	3016.7
All*	Total formula weight	175878.0

*Water molecules are not included.