5AJJ

Crystal structure of variola virus virulence factor F1L in complex with human Bid BH3 domain

5AJJ の概要

• エントリーDOI: 10.2210/pdb5ajj/pdb
• 関連するPDBエントリー: 5AJK
• 分子名称: HOMOLOG OF VACCINIA VIRUS CDS F1L PUTATIVE, BH3-INTERACTING DOMAIN DEATH AGONIST, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: viral protein, bcl-2, apoptosis, poxvirus, bid
• 由来する生物種: VARIOLA VIRUS (SMALLPOX); 詳細
• 細胞内の位置: Cytoplasm . BH3-interacting domain death agonist p15: Mitochondrion membrane . BH3-interacting domain death agonist p13: Mitochondrion membrane . Isoform 1: Cytoplasm. Isoform 3: Cytoplasm. Isoform 2: Mitochondrion membrane: P55957
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 23505.65

構造登録者

Kvansakul, M.,Colman, P.M. (登録日: 2015-02-25, 公開日: 2015-03-25, 最終更新日: 2024-01-10)

• 主引用文献: Marshall, B.,Puthalakath, H.,Caria, S.,Chugh, S.,Doerflinger, M.,Colman, P.M.,Kvansakul, M.; Variola Virus F1L is a Bcl-2-Like Protein that Unlike its Vaccinia Virus Counterpart Inhibits Apoptosis Independent of Bim.; Cell Death Dis., 6:E1680-, 2015; PubMed: 25766319; DOI: 10.1038/CDDIS.2015.52

実験手法

X-RAY DIFFRACTION (1.75 Å)