5AJJ

Crystal structure of variola virus virulence factor F1L in complex with human Bid BH3 domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0033668	biological_process	symbiont-mediated suppression of host apoptosis
A	0042981	biological_process	regulation of apoptotic process
B	0005737	cellular_component	cytoplasm
B	0042981	biological_process	regulation of apoptotic process
B	0043065	biological_process	positive regulation of apoptotic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1202

Chain	Residue
A	TYR83
A	LYS87
A	TYR94
A	HOH2016

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT A 1203

Chain	Residue
A	SER86
A	ARG89
A	PRO174
A	HOH2096

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Functional Information from PROSITE/UniProt

site_id	PS01259
Number of Residues	15
Details	BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. IarhLAqVGDSMDRS

Chain	Residue	Details
B	ILE86-SER100

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Motif: {"description":"BH3","evidences":[{"source":"UniProtKB","id":"P70444","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Site: {"description":"Cleavage","evidences":[{"source":"UniProtKB","id":"P70444","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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