5AB3
S.enterica HisA mutant D7N, D10G, dup13-15, Q24L, G102A
Summary for 5AB3
Entry DOI | 10.2210/pdb5ab3/pdb |
Descriptor | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE, SODIUM ION, ... (4 entities in total) |
Functional Keywords | isomerase, hisa, protein evolution, iad model, trpf |
Biological source | Salmonella enterica subsp. enterica serovar Cubana str. 76814 |
Total number of polymer chains | 3 |
Total formula weight | 84106.21 |
Authors | Guo, X.,Soderholm, A.,Newton, M.,Nasvall, J.,Andersson, D.,Patrick, W.,Selmer, M. (deposition date: 2015-07-31, release date: 2016-09-28, Last modification date: 2024-01-10) |
Primary citation | Newton, M.S.,Guo, X.,Soderholm, A.,Nasvall, J.,Lundstrom, P.,Andersson, D.I.,Selmer, M.,Patrick, W.M. Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes. Proc. Natl. Acad. Sci. U.S.A., 114:4727-4732, 2017 Cited by PubMed: 28416687DOI: 10.1073/pnas.1618552114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.803 Å) |
Structure validation
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