5AB3

S.enterica HisA mutant D7N, D10G, dup13-15, Q24L, G102A

5AB3 の概要

• エントリーDOI: 10.2210/pdb5ab3/pdb
• 分子名称: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: isomerase, hisa, protein evolution, iad model, trpf
• 由来する生物種: Salmonella enterica subsp. enterica serovar Cubana str. 76814
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 84106.21

構造登録者

Guo, X.,Soderholm, A.,Newton, M.,Nasvall, J.,Andersson, D.,Patrick, W.,Selmer, M. (登録日: 2015-07-31, 公開日: 2016-09-28, 最終更新日: 2024-01-10)

• 主引用文献: Newton, M.S.,Guo, X.,Soderholm, A.,Nasvall, J.,Lundstrom, P.,Andersson, D.I.,Selmer, M.,Patrick, W.M.; Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.; Proc. Natl. Acad. Sci. U.S.A., 114:4727-4732, 2017; PubMed: 28416687; DOI: 10.1073/pnas.1618552114

実験手法

X-RAY DIFFRACTION (1.803 Å)