5A3I

Crystal Structure of a Complex formed between FLD194 Fab and Transmissible Mutant H5 Haemagglutinin

5A3I の概要

• エントリーDOI: 10.2210/pdb5a3i/pdb
• 分子名称: HEMAGGLUTININ, ANTI-HAEMAGGLUTININ HA1 FAB HEAVY CHAIN, ANTI-HAEMAGGLUTININ HA1 FAB LIGHT CHAIN, ... (7 entities in total)
• 機能のキーワード: viral protein, haemagglutinin, neutralizing antibody, bird flu, h5n1, influenza virus, glycoprotein
• 由来する生物種: INFLUENZA A VIRUS (A/VIETNAM/1203/2004(H5N1)) (INFLUENZA VIRUS); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 210512.78

構造登録者

Xiong, X.,Corti, D.,Liu, J.,Pinna, D.,Foglierini, M.,Calder, L.J.,Martin, S.R.,Lin, Y.P.,Walker, P.A.,Collins, P.J.,Monne, I.,Suguitan Jr, A.L.,Santos, C.,Temperton, N.J.,Subbarao, K.,Lanzavecchia, A.,Gamblin, S.J.,Skehel, J.J. (登録日: 2015-06-01, 公開日: 2015-07-22, 最終更新日: 2024-01-10)

• 主引用文献: Xiong, X.,Corti, D.,Liu, J.,Pinna, D.,Foglierini, M.,Calder, L.J.,Martin, S.R.,Lin, Y.P.,Walker, P.A.,Collins, P.J.,Monne, I.,Suguitan, A.L.J.,Santos, C.,Temperton, N.J.,Subbarao, K.,Lanzavecchia, A.,Gamblin, S.J.,Skehel, J.J.; Structures of Complexes Formed by H5 Influenza Hemagglutinin with a Potent Broadly Neutralizing Human Monoclonal Antibody.; Proc.Natl.Acad.Sci.USA, 112:9430-, 2015; PubMed: 26170284; DOI: 10.1073/PNAS.1510816112

実験手法

X-RAY DIFFRACTION (2.89 Å)