5A1G
The structure of Human MAT2A in complex with S-adenosylethionine and PPNP.
Summary for 5A1G
| Entry DOI | 10.2210/pdb5a1g/pdb |
| Related | 5A19 5A1I |
| Descriptor | S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2, (4S)-2-METHYL-2,4-PENTANEDIOL, (DIPHOSPHONO)AMINOPHOSPHONIC ACID, ... (8 entities in total) |
| Functional Keywords | transferase, methionine adenosyltransferase, cell growth, liver cancer, methylation |
| Biological source | HOMO SAPIENS (HUMAN) |
| Total number of polymer chains | 1 |
| Total formula weight | 44784.21 |
| Authors | Murray, B.,Antonyuk, S.V.,Marina, A.,Lu, S.C.,Mato, J.M.,Hasnain, S.S.,Rojas, A.L. (deposition date: 2015-04-30, release date: 2016-02-17, Last modification date: 2024-01-10) |
| Primary citation | Murray, B.,Antonyuk, S.V.,Marina, A.,Lu, S.C.,Mato, J.M.,Hasnain, S.S.,Rojas, A.L. Crystallography Captures Catalytic Steps in Human Methionine Adenosyltransferase Enzymes. Proc.Natl.Acad.Sci.USA, 113:2104-, 2016 Cited by PubMed: 26858410DOI: 10.1073/PNAS.1510959113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
Download full validation report
