5A1G
The structure of Human MAT2A in complex with S-adenosylethionine and PPNP.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2 | polymer | 395 | 43720.6 | 1 | UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) | HOMO SAPIENS (HUMAN) | ADOMET SYNTHASE 2, METHIONINE ADENOSYLTRANSFERASE 2, MAT 2, METHIONINE ADENOSYLTRANSFERASE II, MAT-II, METHIONINE ADENOSYLTRANSFERASE 2A |
| 2 | B, C (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 3 | D (A) | (DIPHOSPHONO)AMINOPHOSPHONIC ACID | non-polymer | 257.0 | 1 | Chemie (PPK) | |||
| 4 | E (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 5 | F (A) | [(3S)-3-amino-3-carboxypropyl]{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}ethyls ulfonium | non-polymer | 413.5 | 1 | Chemie (S7M) | |||
| 6 | G (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 7 | H, I (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 8 | J (A) | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43720.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1063.6 | |
| All* | Total formula weight | 44784.2 |
