5A1G

The structure of Human MAT2A in complex with S-adenosylethionine and PPNP.

5A1G の概要

• エントリーDOI: 10.2210/pdb5a1g/pdb
• 関連するPDBエントリー: 5A19 5A1I
• 分子名称: S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2, (4S)-2-METHYL-2,4-PENTANEDIOL, (DIPHOSPHONO)AMINOPHOSPHONIC ACID, ... (8 entities in total)
• 機能のキーワード: transferase, methionine adenosyltransferase, cell growth, liver cancer, methylation
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44784.21

構造登録者

Murray, B.,Antonyuk, S.V.,Marina, A.,Lu, S.C.,Mato, J.M.,Hasnain, S.S.,Rojas, A.L. (登録日: 2015-04-30, 公開日: 2016-02-17, 最終更新日: 2024-01-10)

• 主引用文献: Murray, B.,Antonyuk, S.V.,Marina, A.,Lu, S.C.,Mato, J.M.,Hasnain, S.S.,Rojas, A.L.; Crystallography Captures Catalytic Steps in Human Methionine Adenosyltransferase Enzymes.; Proc.Natl.Acad.Sci.USA, 113:2104-, 2016; PubMed: 26858410; DOI: 10.1073/PNAS.1510959113

実験手法

X-RAY DIFFRACTION (1.83 Å)