5ZJF
LDHA-MA
Summary for 5ZJF
Entry DOI | 10.2210/pdb5zjf/pdb |
Descriptor | L-lactate dehydrogenase A chain, 5,5'-[(2R,3S)-2,3-dimethylbutane-1,4-diyl]bis(2H-1,3-benzodioxole) (3 entities in total) |
Functional Keywords | ldha, inhibitor, machilin a, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 12 |
Total formula weight | 449514.65 |
Authors | Han, C.W.,Jang, S.B. (deposition date: 2018-03-20, release date: 2019-07-24, Last modification date: 2023-11-22) |
Primary citation | Chung, T.-W.,Kim, E.-Y.,Han, C.W.,Park, S.Y.,Jeong, M.S.,Yoon, D.,Choi, H.-J.,Jin, L.,Park, M.-J.,Kwon, Y.J.,Lee, H.,Kim, K.-J.,Park, K.H.,Kim, S.,Jang, S.B.,Ha, K.-T. Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid. Cancers (Basel), 11:-, 2019 Cited by PubMed: 31324019DOI: 10.3390/cancers11070963 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.602 Å) |
Structure validation
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