5Y9J
BAFF in complex with belimumab
Summary for 5Y9J
Entry DOI | 10.2210/pdb5y9j/pdb |
Descriptor | belibumab light chain, belimumab heavy chain, Tumor necrosis factor ligand superfamily member 13B, ... (4 entities in total) |
Functional Keywords | baff, belimumab, antibody, lupus, protein binding |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 64803.42 |
Authors | Heo, Y.-S.,Shin, W. (deposition date: 2017-08-25, release date: 2018-02-21, Last modification date: 2019-09-04) |
Primary citation | Shin, W.,Lee, H.T.,Lim, H.,Lee, S.H.,Son, J.Y.,Lee, J.U.,Yoo, K.Y.,Ryu, S.E.,Rhie, J.,Lee, J.Y.,Heo, Y.S. BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus. Nat Commun, 9:1200-1200, 2018 Cited by PubMed: 29572471DOI: 10.1038/s41467-018-03620-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report