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5W6D

Crystal structure of BG505-SOSIP.v4.1-GT1-N137A in complex with Fabs 35022 and 9H/109L

Summary for 5W6D
Entry DOI10.2210/pdb5w6d/pdb
DescriptorBG505-SOSIP.v4.1-GT1-N137A gp120, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
Functional Keywordshiv-1 broadly neutralizing antibody, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman immunodeficiency virus 1 (HIV-1)
More
Total number of polymer chains6
Total formula weight176226.50
Authors
Garces, F.,Stanfield, R.L.,Wilson, I.A. (deposition date: 2017-06-16, release date: 2017-07-05, Last modification date: 2023-10-04)
Primary citationMedina-Ramirez, M.,Garces, F.,Escolano, A.,Skog, P.,de Taeye, S.W.,Del Moral-Sanchez, I.,McGuire, A.T.,Yasmeen, A.,Behrens, A.J.,Ozorowski, G.,van den Kerkhof, T.L.G.M.,Freund, N.T.,Dosenovic, P.,Hua, Y.,Gitlin, A.D.,Cupo, A.,van der Woude, P.,Golabek, M.,Sliepen, K.,Blane, T.,Kootstra, N.,van Breemen, M.J.,Pritchard, L.K.,Stanfield, R.L.,Crispin, M.,Ward, A.B.,Stamatatos, L.,Klasse, P.J.,Moore, J.P.,Nemazee, D.,Nussenzweig, M.C.,Wilson, I.A.,Sanders, R.W.
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.
J. Exp. Med., 214:2573-2590, 2017
Cited by
PubMed: 28847869
DOI: 10.1084/jem.20161160
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.202 Å)
Structure validation

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