5VZ6

HIV Reverse Transcriptase complexed with (E)-3-(pyrimidin-2-yl)-N-(5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1H-pyrazol-3-yl)acrylamide

Summary for 5VZ6

• Entry DOI: 10.2210/pdb5vz6/pdb
• Descriptor: HIV Reverse Transcriptase, 3-(pyrimidin-2-yl)-N-[3-(5,6,7,8-tetrahydronaphthalen-2-yl)-1H-pyrazol-5-yl]propanamide, ... (4 entities in total)
• Functional Keywords: hiv, rt, reverse transcriptase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Human immunodeficiency virus type 1 (HIV-1); More
• Cellular location: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P04585 P04585
• Total number of polymer chains: 2
• Total formula weight: 116974.15

Authors

Yan, Y.,Su, H.P. (deposition date: 2017-05-26, release date: 2018-05-30, Last modification date: 2024-03-13)

• Primary citation: Yan, Y.,Su, H.P.; HIV Reverse Transcriptase complexed with inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)