5VZ6
HIV Reverse Transcriptase complexed with (E)-3-(pyrimidin-2-yl)-N-(5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1H-pyrazol-3-yl)acrylamide
Summary for 5VZ6
Entry DOI | 10.2210/pdb5vz6/pdb |
Descriptor | HIV Reverse Transcriptase, 3-(pyrimidin-2-yl)-N-[3-(5,6,7,8-tetrahydronaphthalen-2-yl)-1H-pyrazol-5-yl]propanamide, ... (4 entities in total) |
Functional Keywords | hiv, rt, reverse transcriptase, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Human immunodeficiency virus type 1 (HIV-1) More |
Cellular location | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P04585 P04585 |
Total number of polymer chains | 2 |
Total formula weight | 116974.15 |
Authors | |
Primary citation | Yan, Y.,Su, H.P. HIV Reverse Transcriptase complexed with inhibitor To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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