5VYG
Crystal structure of hFA9 EGF repeat with O-glucose trisaccharide
Summary for 5VYG
Entry DOI | 10.2210/pdb5vyg/pdb |
Descriptor | Coagulation factor IX, alpha-D-xylopyranose-(1-3)-alpha-D-xylopyranose-(1-3)-beta-D-glucopyranose, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | notch regulation, egf repeat, glycosylation, transferase-hydrolase complex, transferase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 18584.08 |
Authors | |
Primary citation | Takeuchi, H.,Yu, H.,Hao, H.,Takeuchi, M.,Ito, A.,Li, H.,Haltiwanger, R.S. O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking J. Biol. Chem., 292:15964-15973, 2017 Cited by PubMed: 28729422DOI: 10.1074/jbc.M117.800102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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