5VDH
Crystal Structure of Human Glycine Receptor alpha-3 Bound to AM-3607, Glycine, and Ivermectin
Summary for 5VDH
Entry DOI | 10.2210/pdb5vdh/pdb |
Related | 5VDI |
Descriptor | Glycine receptor subunit alpha-3, (3S,3aS,9bS)-2-[(2H-1,3-benzodioxol-5-yl)sulfonyl]-3,5-dimethyl-1,2,3,3a,5,9b-hexahydro-4H-pyrrolo[3,4-c][1,6]naphthyridin-4-one, GLYCINE, ... (8 entities in total) |
Functional Keywords | ligand-gated ion channel, neurotransmitter receptor, membrane protein, cys-loop receptor, transport protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 216628.70 |
Authors | Shaffer, P.L.,Huang, X.,Chen, H. (deposition date: 2017-04-03, release date: 2017-05-24, Last modification date: 2023-10-04) |
Primary citation | Huang, X.,Chen, H.,Shaffer, P.L. Crystal Structures of Human GlyR alpha 3 Bound to Ivermectin. Structure, 25:945-950.e2, 2017 Cited by PubMed: 28479061DOI: 10.1016/j.str.2017.04.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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