5UV8

Interleukin-3 Receptor Complex

Summary for 5UV8

Entry DOI	10.2210/pdb5uv8/pdb
Descriptor	Interleukin-3 receptor subunit alpha, Interleukin-3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	receptor, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	97324.76
Authors	Broughton, S.E.,Parker, M.W. (deposition date: 2017-02-19, release date: 2018-02-07, Last modification date: 2023-10-04)
Primary citation	Broughton, S.E.,Hercus, T.R.,Nero, T.L.,Kan, W.L.,Barry, E.F.,Dottore, M.,Cheung Tung Shing, K.S.,Morton, C.J.,Dhagat, U.,Hardy, M.P.,Wilson, N.J.,Downton, M.T.,Schieber, C.,Hughes, T.P.,Lopez, A.F.,Parker, M.W. A dual role for the N-terminal domain of the IL-3 receptor in cell signalling. Nat Commun, 9:386-386, 2018 Cited by PubMed: 29374162 DOI: 10.1038/s41467-017-02633-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation