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5OUA

Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compound RKp017

Summary for 5OUA
Entry DOI10.2210/pdb5oua/pdb
DescriptorcAMP-dependent protein kinase catalytic subunit alpha, cAMP dependent protein kinase inhibitor, beta-D-ribopyranose, ... (4 entities in total)
Functional Keywordscomplex, peptidic ligand, transferase
Biological sourceCricetulus griseus (Chinese hamster)
More
Total number of polymer chains2
Total formula weight43317.05
Authors
Mueller, J.M.,Heine, A.,Klebe, G. (deposition date: 2017-08-23, release date: 2018-09-05, Last modification date: 2024-10-23)
Primary citationMueller, J.M.,Kirschner, R.,Geyer, A.,Klebe, G.
Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage
Acs Omega, 2019
Cited by
DOI: 10.1021/acsomega.8b02364
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.67 Å)
Structure validation

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