5OCM
Imine Reductase from Streptosporangium roseum in complex with NADP+ and 2,2,2-trifluoroacetophenone hydrate
Summary for 5OCM
Entry DOI | 10.2210/pdb5ocm/pdb |
Descriptor | NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2,2,2-trifluoromethyl acetophenone hydrate, ... (5 entities in total) |
Functional Keywords | imine, amine, nadph, oxidoreductase |
Biological source | Streptosporangium roseum |
Total number of polymer chains | 6 |
Total formula weight | 186027.42 |
Authors | Sharma, M.,Nestl, B.,Grogan, G. (deposition date: 2017-07-03, release date: 2018-05-16, Last modification date: 2024-01-17) |
Primary citation | Lenz, M.,Fademrecht, S.,Sharma, M.,Pleiss, J.,Grogan, G.,Nestl, B.M. New imine-reducing enzymes from beta-hydroxyacid dehydrogenases by single amino acid substitutions. Protein Eng. Des. Sel., 31:109-120, 2018 Cited by PubMed: 29733377DOI: 10.1093/protein/gzy006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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