5NXQ
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to a stapled Sld5 CIP
Summary for 5NXQ
Entry DOI | 10.2210/pdb5nxq/pdb |
Related | 4C8S 4C95 |
Descriptor | DNA polymerase alpha-binding protein, MET-ASP-ILE-UA1-ILE-ASP-ASP-ILE-LEU-UA2-GLU-LEU-ASP-LYS-GLU, GLYCEROL, ... (4 entities in total) |
Functional Keywords | dna replication, adaptor protein, beta-propeller domain, replication |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Cellular location | Nucleus: Q01454 |
Total number of polymer chains | 5 |
Total formula weight | 168315.01 |
Authors | Wu, Y.,Pellegrini, L. (deposition date: 2017-05-10, release date: 2017-08-30, Last modification date: 2024-01-17) |
Primary citation | Wu, Y.,Villa, F.,Maman, J.,Lau, Y.H.,Dobnikar, L.,Simon, A.C.,Labib, K.,Spring, D.R.,Pellegrini, L. Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design. Angew. Chem. Int. Ed. Engl., 56:12866-12872, 2017 Cited by PubMed: 28815832DOI: 10.1002/anie.201705611 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.413 Å) |
Structure validation
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