5NXQ

Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to a stapled Sld5 CIP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	DNA polymerase alpha-binding protein	polymer	479	54534.6	3	UniProt (Q01454) Pfam (PF12341) Pfam (PF20946)	Saccharomyces cerevisiae (Baker's yeast)	Chromosome replication protein CHL15,Chromosome transmission fidelity protein 4,Protein POB1
2	D, E (D, E)	MET-ASP-ILE-UA1-ILE-ASP-ASP-ILE-LEU-UA2-GLU-LEU-ASP-LYS-GLU	polymer	19	2309.6	2	UniProt (by SIFTS) (Q03406)	Saccharomyces cerevisiae
3	F (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	G, H, I, J, K (A, B, C, D, E)	water	water		18.0	336	Chemie (HOH)

Sequence modifications

A, B, C: 471 - 927 (UniProt: Q01454)

PDB	External Database	Details
Met 449	-	initiating methionine
Gly 450	-	expression tag
Ser 451	-	expression tag
Ser 452	-	expression tag
His 453	-	expression tag
His 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag
Ser 459	-	expression tag
Gln 460	-	expression tag
Asp 461	-	expression tag
Pro 462	-	expression tag
Glu 463	-	expression tag
Asn 464	-	expression tag
Leu 465	-	expression tag
Tyr 466	-	expression tag
Phe 467	-	expression tag
Gln 468	-	expression tag
Gly 469	-	expression tag
Ser 470	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	168222.9
Non-Polymers*	Number of molecules	1
	Total formula weight	92.1
All*	Total formula weight	168315.0

*Water molecules are not included.