5NHU
HUMAN ALPHA THROMBIN COMPLEXED WITH ANOPHELES GAMBIAE cE5 ANTICOAGULANT
Summary for 5NHU
Entry DOI | 10.2210/pdb5nhu/pdb |
Descriptor | Prothrombin, AGAP008004-PA, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | blood clotting, anticoagulant, thrombin, inhibitor, hydrolase |
Biological source | Anopheles gambiae (African malaria mosquito) More |
Total number of polymer chains | 9 |
Total formula weight | 129176.84 |
Authors | Ripoll-Rozada, J.,Pereira, P.J.B. (deposition date: 2017-03-22, release date: 2017-06-14, Last modification date: 2024-01-17) |
Primary citation | Pirone, L.,Ripoll-Rozada, J.,Leone, M.,Ronca, R.,Lombardo, F.,Fiorentino, G.,Andersen, J.F.,Pereira, P.J.B.,Arca, B.,Pedone, E. Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae. J. Biol. Chem., 292:12632-12642, 2017 Cited by PubMed: 28592490DOI: 10.1074/jbc.M117.788042 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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