5LP6
Crystal structure of Tubulin-Stathmin-TTL-Thiocolchicine Complex
Summary for 5LP6
Entry DOI | 10.2210/pdb5lp6/pdb |
Descriptor | Tubulin alpha-1B chain, ~{N}-[(7~{R})-1,2,3-trimethoxy-10-methylsulfanyl-9-oxidanylidene-6,7-dihydro-5~{H}-benzo[a]heptalen-7-yl]ethanamide, CALCIUM ION, ... (12 entities in total) |
Functional Keywords | microtubules, thiocolchicine, tubulin, tubulin-tyrosine ligase, structural protein |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 6 |
Total formula weight | 261968.55 |
Authors | Marangon, J.,Christodoulou, M.,Casagrande, F.,Tiana, G.,Dalla Via, L.,Aliverti, A.,Passarella, D.,Cappelletti, G.,Ricagno, S. (deposition date: 2016-08-11, release date: 2016-09-21, Last modification date: 2024-01-10) |
Primary citation | Marangon, J.,Christodoulou, M.S.,Casagrande, F.V.,Tiana, G.,Dalla Via, L.,Aliverti, A.,Passarella, D.,Cappelletti, G.,Ricagno, S. Tools for the rational design of bivalent microtubule-targeting drugs. Biochem. Biophys. Res. Commun., 479:48-53, 2016 Cited by PubMed: 27613098DOI: 10.1016/j.bbrc.2016.09.022 PDB entries with the same primary citation |
Experimental method |
Structure validation
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