5K6I
Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 A149C-Y458C, S46G-E92D-S215P-K465Q variant.
Summary for 5K6I
Entry DOI | 10.2210/pdb5k6i/pdb |
Related | 5K6B 5K6C 5K6F 5K6G 5K6H |
Descriptor | Fusion glycoprotein F0, ZINC ION, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | respiratory syncytial virus, prefusion, vaccine, stabilized, viral protein |
Biological source | Human respiratory syncytial virus A (strain A2) |
Total number of polymer chains | 1 |
Total formula weight | 49974.44 |
Authors | Joyce, M.G.,Zhang, B.,Mascola, J.R.,Kwong, P.D. (deposition date: 2016-05-24, release date: 2016-08-17, Last modification date: 2020-07-29) |
Primary citation | Joyce, M.G.,Zhang, B.,Ou, L.,Chen, M.,Chuang, G.Y.,Druz, A.,Kong, W.P.,Lai, Y.T.,Rundlet, E.J.,Tsybovsky, Y.,Yang, Y.,Georgiev, I.S.,Guttman, M.,Lees, C.R.,Pancera, M.,Sastry, M.,Soto, C.,Stewart-Jones, G.B.,Thomas, P.V.,Van Galen, J.G.,Baxa, U.,Lee, K.K.,Mascola, J.R.,Graham, B.S.,Kwong, P.D. Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23:811-820, 2016 Cited by PubMed: 27478931DOI: 10.1038/nsmb.3267 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.92 Å) |
Structure validation
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