5J11
Structure of human TSLP in complex with TSLPR and IL-7Ralpha
Summary for 5J11
Entry DOI | 10.2210/pdb5j11/pdb |
Descriptor | Thymic stromal lymphopoietin, Interleukin-7 receptor subunit alpha, Cytokine receptor-like factor 2, ... (6 entities in total) |
Functional Keywords | cytokine inflammation tslp signaling complex, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 71282.23 |
Authors | Verstraete, K.,Savvides, S.N. (deposition date: 2016-03-28, release date: 2017-04-05, Last modification date: 2024-01-10) |
Primary citation | Verstraete, K.,Peelman, F.,Braun, H.,Lopez, J.,Van Rompaey, D.,Dansercoer, A.,Vandenberghe, I.,Pauwels, K.,Tavernier, J.,Lambrecht, B.N.,Hammad, H.,De Winter, H.,Beyaert, R.,Lippens, G.,Savvides, S.N. Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma. Nat Commun, 8:14937-14937, 2017 Cited by PubMed: 28368013DOI: 10.1038/ncomms14937 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.56 Å) |
Structure validation
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