5IGN
Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe
Summary for 5IGN
Entry DOI | 10.2210/pdb5ign/pdb |
Descriptor | Bromodomain-containing protein 9, N-[(2R,3S)-2-(4-chlorophenyl)-1-(1,4-dimethyl-2-oxo-1,2-dihydroquinolin-7-yl)-6-oxopiperidin-3-yl]-2-methylpropane-1-sulfonamide (3 entities in total) |
Functional Keywords | lysine-acetylated histone binding, chromatin regulator, transcription, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 29531.63 |
Authors | Tallant, C.,Clark, P.G.K.,Vieira, L.C.C.,Newman, J.A.,Krojer, T.,Nunez-Alonso, G.,Picaud, S.,Fedorov, O.,Dixon, D.J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Brennan, P.E.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2016-02-28, release date: 2016-03-30, Last modification date: 2024-01-10) |
Primary citation | Tallant, C.,Clark, P.G.K.,Vieira, L.C.C.,Krojer, T.,Nunez-Alonso, G.,Picaud, S.,Fedorov, O.,Dixon, D.J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Brennan, P.E.,Knapp, S. Crystal structure of BRD9 bromodomain in complex with LP99 chemical probe To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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