5IGN
Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue 6B2 A 201 |
| Chain | Residue |
| A | HIS42 |
| A | TYR106 |
| A | LYS123 |
| A | HOH308 |
| B | LEU127 |
| B | SER134 |
| A | GLY43 |
| A | PHE44 |
| A | PHE45 |
| A | PHE47 |
| A | PRO48 |
| A | THR50 |
| A | ILE53 |
| A | ASN100 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue 6B2 B 201 |
| Chain | Residue |
| B | PRO41 |
| B | HIS42 |
| B | HIS42 |
| B | GLY43 |
| B | PHE44 |
| B | PHE47 |
| B | PRO48 |
| B | THR50 |
| B | THR50 |
| B | ILE53 |
| B | ALA54 |
| B | ASN100 |
| B | TYR106 |
| B | HOH313 |
| B | HOH326 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Region: {"description":"Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding","evidences":[{"source":"PubMed","id":"26365797","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding","evidences":[{"source":"PubMed","id":"26365797","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
