5IGN
Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bromodomain-containing protein 9 | polymer | 123 | 14249.8 | 2 | UniProt (Q9H8M2) Pfam (PF00439) In PDB | Homo sapiens (Human) | Rhabdomyosarcoma antigen MU-RMS-40.8 |
| 2 | A, B | N-[(2R,3S)-2-(4-chlorophenyl)-1-(1,4-dimethyl-2-oxo-1,2-dihydroquinolin-7-yl)-6-oxopiperidin-3-yl]-2-methylpropane-1-sulfonamide | non-polymer | 516.1 | 2 | Chemie (6B2) | |||
| 3 | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A, B: 14 - 134 (UniProt: Q9H8M2)
| PDB | External Database | Details |
|---|---|---|
| Ser 12 | - | expression tag |
| Met 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28499.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1032.1 | |
| All* | Total formula weight | 29531.6 |
