5HZW
Crystal structure of the orphan region of human endoglin/CD105 in complex with BMP9
Summary for 5HZW
| Entry DOI | 10.2210/pdb5hzw/pdb |
| Related | 5HZV 5I04 5I05 |
| Related PRD ID | PRD_900001 |
| Descriptor | Maltose-binding periplasmic protein,Endoglin, Growth/differentiation factor 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (4 entities in total) |
| Functional Keywords | orphan domain, angiogenesis, glycoprotein, receptor, signaling protein |
| Biological source | Escherichia coli K12 More |
| Total number of polymer chains | 2 |
| Total formula weight | 88028.85 |
| Authors | Bokhove, M.,Saito, T.,Jovine, L. (deposition date: 2016-02-03, release date: 2017-06-07, Last modification date: 2024-01-10) |
| Primary citation | Saito, T.,Bokhove, M.,Croci, R.,Zamora-Caballero, S.,Han, L.,Letarte, M.,de Sanctis, D.,Jovine, L. Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1. Cell Rep, 19:1917-1928, 2017 Cited by PubMed: 28564608DOI: 10.1016/j.celrep.2017.05.011 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (4.451 Å) |
Structure validation
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