5HT2

Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with 1-N6-etheno-adenine

Summary for 5HT2

• Entry DOI: 10.2210/pdb5ht2/pdb
• Related: 4GZ1 5INK 5INL 5INM 5INN 5INO 5INP 5INQ
• Descriptor: Tyrosyl-DNA phosphodiesterase 2, DNA, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: hydrolase, dna repair, endonuclease/exonuclease/phosphatase (eep) domain, hydrolase-dna complex, hydrolase/dna
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 4
• Total formula weight: 63755.49

Authors

Schellenberg, M.J.,Vilas, C.K.,Williams, R.S. (deposition date: 2016-01-26, release date: 2016-04-27, Last modification date: 2024-03-13)

• Primary citation: Schellenberg, M.J.,Perera, L.,Strom, C.N.,Waters, C.A.,Monian, B.,Appel, C.D.,Vilas, C.K.,Williams, J.G.,Ramsden, D.A.,Williams, R.S.; Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.; Nucleic Acids Res., 44:3829-3844, 2016; PubMed: 27060144; DOI: 10.1093/nar/gkw228

Experimental method

X-RAY DIFFRACTION (1.43 Å)