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5HT2

Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with 1-N6-etheno-adenine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Tyrosyl-DNA phosphodiesterase 2polymer25628905.22UniProt (Q9JJX7)
Pfam (PF03372)
Mus musculus (house mouse)Tyr-DNA phosphodiesterase 2,5'-tyrosyl-DNA phosphodiesterase,5'-Tyr-DNA phosphodiesterase,TRAF and TNF receptor-associated protein
2C, D
(C, D)
DNApolymer92763.82Escherichia coli
3E, F, I
(A, B)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
4G
(B)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
5H
(B)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
6J, K, L, M
(A, B, C, D)
waterwater18.0702Chemie (HOH)
Sequence modifications
A, B: 118 - 370 (UniProt: Q9JJX7)
PDBExternal DatabaseDetails
Ser 115-expression tag
Lys 116-expression tag
Gly 117-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight63338.2
Non-Polymers*Number of molecules5
Total formula weight417.3
All*Total formula weight63755.5
*Water molecules are not included.

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PDB entries from 2025-07-02

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