5HHM

Crystal Structure of the JM22 TCR in complex with HLA-A*0201 in complex with M1-F5L

Summary for 5HHM

• Entry DOI: 10.2210/pdb5hhm/pdb
• Related: 5HHN 5HHO 5HHP 5HHQ
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, M1-F5L, GILGLVFTL, ... (6 entities in total)
• Functional Keywords: hla a*0201, influenza, m1, tcr, t cell, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted : P61769
• Total number of polymer chains: 10
• Total formula weight: 188108.82

Authors

Gras, S.,Josephs, T.M.,Rossjohn, J. (deposition date: 2016-01-11, release date: 2016-03-23, Last modification date: 2023-09-27)

• Primary citation: Valkenburg, S.A.,Josephs, T.M.,Clemens, E.B.,Grant, E.J.,Nguyen, T.H.,Wang, G.C.,Price, D.A.,Miller, A.,Tong, S.Y.,Thomas, P.G.,Doherty, P.C.,Rossjohn, J.,Gras, S.,Kedzierska, K.; Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.; Proc.Natl.Acad.Sci.USA, 113:4440-4445, 2016; PubMed: 27036003; DOI: 10.1073/pnas.1603106113

Experimental method

X-RAY DIFFRACTION (2.5 Å)