5H8F

Structure of the apo human GluN1/GluN2A LBD

Summary for 5H8F

Entry DOI	10.2210/pdb5h8f/pdb
Related	5H8H 5H8N 5H8Q 5H8R 5H8S
Descriptor	Glutamate receptor ionotropic, NMDA 2A, Glutamate receptor ionotropic, NMDA 1, GLYCEROL, ... (6 entities in total)
Functional Keywords	glun1, glun2a, nmda, receptor, transport protein
Biological source	Homo sapiens (Human) More
Cellular location	Cell membrane ; Multi-pass membrane protein : Q12879 Q05586
Total number of polymer chains	2
Total formula weight	66067.27
Authors	Wallweber, H.J.A.,Lupardus, P.J. (deposition date: 2015-12-23, release date: 2016-02-24, Last modification date: 2023-09-27)
Primary citation	Hackos, D.H.,Lupardus, P.J.,Grand, T.,Chen, Y.,Wang, T.M.,Reynen, P.,Gustafson, A.,Wallweber, H.J.,Volgraf, M.,Sellers, B.D.,Schwarz, J.B.,Paoletti, P.,Sheng, M.,Zhou, Q.,Hanson, J.E. Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function. Neuron, 89:983-999, 2016 Cited by PubMed: 26875626 DOI: 10.1016/j.neuron.2016.01.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation