5GMG
Crystal structure of monkey TLR7 in complex with loxoribine and polyU
Summary for 5GMG
Entry DOI | 10.2210/pdb5gmg/pdb |
Related | 5GMF 5GMH |
Descriptor | Toll-like receptor 7, RNA (5'-R(P*UP*UP*UP*U)-3'), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | immune system, tlr7, innate immunity, ssrna recogniton, immune system-rna complex, immune system/rna |
Biological source | Macaca mulatta (Rhesus macaque) More |
Total number of polymer chains | 4 |
Total formula weight | 193338.35 |
Authors | Zhang, Z.,Ohto, U.,Shimizu, T. (deposition date: 2016-07-14, release date: 2016-11-02, Last modification date: 2023-11-08) |
Primary citation | Zhang, Z.,Ohto, U.,Shibata, T.,Krayukhina, E.,Taoka, M.,Yamauchi, Y.,Tanji, H.,Isobe, T.,Uchiyama, S.,Miyake, K.,Shimizu, T. Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA Immunity, 45:737-748, 2016 Cited by PubMed: 27742543DOI: 10.1016/j.immuni.2016.09.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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