5E8M
Crystal structure of human heparanase
Summary for 5E8M
Entry DOI | 10.2210/pdb5e8m/pdb |
Descriptor | Heparanase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | glycoside hydrolase, apo, protein, sugar, hydrolase |
Biological source | Homo sapiens (Human) More |
Cellular location | Lysosome membrane; Peripheral membrane protein: Q9Y251 Q9Y251 |
Total number of polymer chains | 2 |
Total formula weight | 54565.65 |
Authors | Wu, L.,Davies, G.J. (deposition date: 2015-10-14, release date: 2015-11-18, Last modification date: 2020-07-29) |
Primary citation | Wu, L.,Viola, C.M.,Brzozowski, A.M.,Davies, G.J. Structural characterization of human heparanase reveals insights into substrate recognition. Nat.Struct.Mol.Biol., 22:1016-1022, 2015 Cited by PubMed: 26575439DOI: 10.1038/nsmb.3136 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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