5DAK
Crystal Structure of human Glutathione Transferase Pi complexed with a metalloid in the absence of Glutathione
Summary for 5DAK
Entry DOI | 10.2210/pdb5dak/pdb |
Related | 5DAL 5DCG 5DDL |
Descriptor | Glutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ARSENIC, ... (5 entities in total) |
Functional Keywords | transferase, metalloid, anti-cancer |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : P09211 P09211 |
Total number of polymer chains | 2 |
Total formula weight | 47311.86 |
Authors | Parker, L.J.,Parker, M.W.,Morton, C.J. (deposition date: 2015-08-20, release date: 2016-12-07, Last modification date: 2023-11-15) |
Primary citation | Parker, L.J.,Parker, M.W.,Morton, C.J.,Bocedi, A.,Ascher, D.B.,Aitken, J.B.,Harris, H.H.,Lo Bello, M.,Ricci, G. Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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